The Impact of Dental Care Before and After Head and Neck Radiotherapy

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Autores: ALEXANDRE FRASCINO, KARIN SÁ FERNANDES, CAROLINA MUSSI, MARINA GALLOTTINI
Data da Publicação 01/02/2014

Publicações
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Volume
117

Edição
2

Páginas
e225

Editora
Elsevier

Descrição

This study evaluated the histopathological features of chronic periapical lesions and adjacent bone tissue in animals treated with zolendronate.
Study Design:
Forty male rats were used. Initially, the pulps of the first mandibular molars were exposed. Subsequently, the animals were divided into 8 groups: GI and GII-Periapical lesion induction (PLI) and weekly intraperitoneal administration (WIPA) of saline solution for 4 and 8 weeks, respectively; GIII and GIVePLI and WIPA of zolendronate (0.15 mg/kg/week) for 4 and 8 weeks; GV and GVIeWIPA of saline solution for 4 and 8 weeks and subsequent PLI; GVII and GVIIIWIPA of zolendronate for 4 and 8 weeks and subsequent PLI.

Results:

Periapical lesions were characterized by chronic inflammation, with no difference between groups. No osteonecrosis was observed in any specimen.

Conclusion:
Chronic periapical lesions apparently are not a risk factor for …

Artigos do Google Acadêmico
The Impact of Dental Care Before and After Head and Neck Radiotherapy
A FRASCINO, KSÁ FERNANDES, C MUSSI… - Oral Surgery, Oral Medicine, Oral Pathology and Oral …, 2014

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